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Image Search Results
Journal: Bioactive Materials
Article Title: An injectable and coagulation-independent Tetra-PEG hydrogel bioadhesive for post-extraction hemostasis and alveolar bone regeneration
doi: 10.1016/j.bioactmat.2024.03.015
Figure Lengend Snippet: The in vitro adhesive properties and biocompatibility of the Tetra-PEG hydrogel. (A) Photographs of the in situ formation hydrogel onto the porcine mucosal tissue that suffers from different deformations (scale bar: 2 cm). (B) Lap shear strength of the Tetra-PEG hydrogel in its initial state and after equilibrium swelling in DI water, AS, and AB, respectively (n = 3). (C, D) The representative SEM (C) and H&E-stained (D) images of the adhesion interfaces between the rat tissues (gingiva and alveolar bone) and hydrogel (scale bar: 100 μm). In SEM images, the white dotted area represents the fractured hydrogel-tissue interface, and the red circle indicates the remaining entanglements after freeze-fractured. (E) Comparison of the in vitro sealing abilities of the Tetra-PEG hydrogel and gelatin sponge using a porcine jaw filled with anticoagulated blood. (F, G) Cell viability (F) and LIVE/DEAD assay images (G) of HGFs and BMSCs against the hydrogel, respectively (n = 5, scale bar: 300 μm). All data are presented as the mean ± S.D.
Article Snippet: The human gingival fibroblasts (HGFs) (Procell, China) and
Techniques: In Vitro, Adhesive, In Situ, Shear, Staining, Comparison, Live Dead Assay